Stephanie Sherman is Professor Emerita in the Department of Human Genetics at Emory University. She has focused her research on identifying the causes and consequences of trisomy 21, with a special emphasis on discovering genetic and environmental factors that explain the severity of the associated clinical conditions. With the work of the Down syndrome community and funds from the NIH INCLUDE Initiative and the Gabriella Miller Kids First Pediatric Research Program, she and her colleagues have organized a repository of whole genome sequencing and clinical data on about 2000 people with Down syndrome that will soon be available to the scientific community. She is a member of the National Down Syndrome Society’s Science and Advisory Board. She is the Chair of the Child Development and Clinical Committee of the Trisomy 21 Research Society and a member of the T21RS COVID-19 Taskforce.